Indication

Dysentery, Diarrhoea, Gastroenteritis, Biliary colic, Enterocolitis, Cholecystitis, Colonopathies, Mild cystitis and spasmodic dysmenorrhoea, Visceral muscle spasm

Adult Dose

Oral Adult Tablet: The usual dosages are 2 to 6 tablets (100-300 mg) daily in divided doses as required. Parenteral Injection: 1 ampoule by slow IV/IM injection 3 times daily.

Contraindication

This drug must not be used in glaucoma (acute pain in the eyeball with disorders of vision), difficulties in urinating (disorders of the prostate or bladder).

Mode of Action

Tiemonium Methylsulfate) is a synthetic anticholinergic-antispasmodic drug. Tiemonium are quaternary ammonium antimuscarinic agent with peripheral effect similar to those of atropine. Tiemonium strengthens calcium bonding with phospho lipids and proteins thus stabilizing the cell membrane of the GI tract.

Precaution

Precautions should be exercised for treatment of patients with disorders of the prostate, serious diseases of the kidney or liver, cardiac disorders, thyroid disorders, chronic bronchitis and certain gastrointestinal diseases. The risks of visual disturbances can make it dangerous to drive or use machines.

Side Effect

Tiemonium Methylsulfate INN may have some undesirable effects in certain individuals like risk of hypotension and tachycardia especially in case of injection.